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Given the importance of hyperandrogenism-hyperinsulinemia in PCOS, most of the current therapeutic strategies aim at reducing androgen excess by improving insulin sensitivity, mainly via lifestyle changes and/or pharmacological approaches

Jones IR, Owens DR, Luzio S, Williams S, Hayes TM

Week Two to Three: Peak Side Effects and Adaptation Strategies Weeks two and three represent the most challenging period for many patients, as side effects often intensify before beginning to fade