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Blood glucose levels (mg/dl, measured with Accucheck guide glucometer (Roche, Basel, Switzerland)) were measured after 15, 30, 60, and 120 min of glucose injection

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The R groups that can be protonated/deprotonated include Lys, Arg, and His, which have a + 1 charge when protonated, and Glu and Asp (carboxylic acids), Tyr and Ser (alcohols), and Cys (thiol), which have zero charges when protonated