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Medication adjustments may be considered in consultation with prescribing clinicians: Dose reduction : Lowering the Ozempic dose may reduce symptom severity whilst maintaining some glycaemic benefit Slower titration : Increasing the dose more gradually than standard protocols may improve tolerability Prokinetic agents : In the UK, medications such as metoclopramide are generally restricted to short-term use (maximum 5 days) due to neurological side effect risks

Deionized Water, Lecithin Phospholipids, L-Glutathione, Alcohol (ethanol), Potassium Hydroxide (for pH adjustment)

Pharmacokinetics of IL-18 Binding Protein in Healthy Volunteers and Subjects With Rheumatoid Arthritis or Plaque Psoriasis