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In this same trial, taking semaglutide was associated with reduced risk factors for cardiovascular disease, including blood pressure, waist circumference, lipids, and inflammatory markers

The combination of nivolumab and ipilimumab has been subsequently evaluated in non-cutaneous melanoma including acral, mucosal, and uveal melanoma, and the combination regimen shows sustained and improved response compared with either single agent, although with elevated toxicity but manageable safety profile

At the same time, they also reported that the number of patients with one episode of hypoglycemia in the saxagliptin group was 1.9% higher than that in the placebo group

A landscape report published in Frontiers in Immunology in October highlighted 56 ongoing CAR-T trials for autoimmune rheumatic diseases, with most in Phase I but some in Phase II