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Mouse anti-Fas monoclonal antibody (#8023, diluted 1:1,000), mouse anti-Caspase-8 monoclonal antibody (#9746, diluted 1:1000), and rabbit anti-AIFM2/FSP1 polyclonal antibody (#24972, diluted 1:1000) (for endogenous FSP1 detection) were obtained from Cell Signaling Technology

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Epacadostat plus pembrolizumab versus placebo plus pembrolizumab in patients with unresectable or metastatic melanoma (ECHO-301/KEYNOTE-252): a phase 3, randomised, double-blind study

In chronic prostatitis, ROS induce lipid peroxidation of cell membranes, disrupt the barrier function of cells, and damage mitochondria, leading to energy metabolism disorders