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The 2.4 mg group lost the most weight, which means that among adults suffering from overweight or obesity and T2DM, SMG 2.4 mg once a week has achieved significant clinically significant weight loss ( 2 (or 27 kg/m 2 with more than 1 body weight-related coexisting disease)

682-P: Novel dual glucagon and glucagon-like peptide-1 receptor agonist LY3305677 improves glucose control, reduces body weight, and increases energy expenditure in mice

This significantly decreases appetite hormones

Plaintiffs argue that these drugs cause gastroparesis, while the defense counters that the drugs are designed to delay gastric emptying, which is different from gastroparesis