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Pickles S, Vigi P, Youle RJ

, myeloperoxidase, leukotriene B4, tromboxane B2) (44), interacts with prostaglandin-dependent pathways (45, 46), has a direct protective and proliferative effect on target cells (18, 19), and modulates the release of nitric oxide (27)

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Exedin-4, a naturally occurring GLP-1RA derived from Gila monster venom, has also been shown to suppress macrophage-driven inflammation by enhancing adiponectin expression