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Nutrients (2017) 9(8):866

Immunomodulatory actions of vitamin D The active form of vitamin D, calcitriol (1,25(OH)D), acts as a potent immunomodulator by binding to vitamin D receptors (VDR) expressed on immune cells [41, 42]

ROS probes further confirmed that uricase generated a higher level of ROS during UA degradation, whereas PDA@Pt does not (Fig

Such studies have shown BBB dysfunction in patients with AD and other neurodegenerative disorders such as PD, ALS, and MS, which is also supported by biofluid biomarker data and postmortem studies [190]