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While semaglutide can cause weight loss without lifestyle changes, NICE guidelines specify it should be used alongside diet and exercise modifications

Include probiotic-rich foods such as kefir, yogurt, or kimchi to help restore a healthy balance of gut bacteria, supporting bowel function

Glucagon-like peptide-1 was identified as a potent insulinotropic factor in the 1980s

Some people may notice positive changes in their appetite, such as reduced cravings or feeling more satisfied between meals, within a few weeks, but the most significant results are likely to happen when you reach the maintenance dose from around week 13 of treatment