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The impact of NAC on the metabolome of lupus PBL was further evaluated by pathway analysis comparing pre-treatment samples obtained at visit 1 to samples obtained at visits 24 during biologically and clinical effective administration of NAC at doses of 2.4 and 4.8 g/day

at the highest doses, gastrointestinal adverse events affected over 50% of participants, with most episodes mild to moderate

Patients should always discuss potential risks with their healthcare provider before starting semaglutide treatment