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Description

Inducing a calorie deficit that often results in rapid weight loss

Men and women and female and male rodents lose weight and eat less in response to GLP-1 and its analogs

The prebiotic inulin improves substrate metabolism and promotes short-chain fatty acid production in overweight to obese men

Overall, this study shows that replacing four consecutives amino acid residues with an ureido triad of similar dimension and geometry in a peptide -helix is a good strategy to improve its pharmaceutical properties