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Zudem verlangsamt es die Magenentleerung, was dazu beitrgt, den Appetit zu regulieren, indem das Sttigungsgefhl lnger anhlt

Rotate to a different site at least each week, and within each body area (abdomen, thigh, or arm), vary the exact spot to prevent lipohypertrophy

Discuss with your clinician about adjusting your GLP-1 dosing schedule if constipation is severe Consider prescription medications for persistent constipation that doesnt respond to other measures When to seek medical advice Contact your healthcare provider if you experience: No bowel movement for more than 4-5 days Severe abdominal pain or distension Blood in the stool Constipation alternating with diarrhoea Unexplained weight loss or fatigue Constipation that doesnt improve with self-management strategies Long-term outlook For most patients, constipation either resolves as the body adjusts to GLP-1 therapy or can be effectively managed with dietary and lifestyle modifications

Ann Intern Med 178(6):898900