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Dutta et al

Trends Immunol 2024, 45: 329337

The substantial reductions in BP observed following treatment with CagriSema 2.4 mg/2.4 mg are likely to lead to a reduced risk of developing cardiovascular diseaserelated illnesses, such as heart failure, stroke, and chronic kidney disease, and represent an important advance for patients with obesity-related hypertension

Based on these limitations, we propose that future research should focus on the following specific directions: clarifying the upstream regulation mechanism, developing more complex experimental models, and promoting the transformation of clinical to precision medicine