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Combination Approaches Combining glutaminase inhibitors with standard therapies may boost effectiveness

However, in patients with T2D, metabolic syndrome has shown to predict atherosclerosis, is an independent predictor of cardiovascular disease, is an indicator of microvascular and macrovascular complications and increased risk of adverse cardio-renal outcomes [58,59,60,61]

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This novel dual-agonist approach surpassed the efficacy of monotherapy while maintaining a favorable costbenefit and safety profile [122]