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One 2024 study at the Smell and Taste Center at the University of Pennsylvania (source) found evidence of GLP1 agonists significantly depressing the perception of all five basic taste qualities. Interestingly, while all participants in the study experienced a slight decline in their sense of smell, it was not considered statistically significant suggesting that olfactory changes may be more individualised, or more complex to detect in standardised tests
They were still losing at week 68
E., Halliwell, B
Summary: Feeling worse after a B12 injection typically reflects your body adjusting to replenished vitamin levels, triggering metabolic processes that may temporarily cause fatigue, headaches, or injection site discomfort
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