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Think of it as a bouncer at a club, not letting any new trouble start

This work was financially supported by grants from the Research Council of Finland (grant 315351 to PR, grant 266621 to HR, grant 321564 to VT, and grant 333284 to RK), the Sigrid Juslius Foundation (to PR, HR, VT, and RK), the Finnish Cultural Foundation (to PR and LP), Drug Research Doctoral Programme (to AS), the Finnish Foundation for Cardiovascular Research (to LP, HR, VT, RK, and PR), the Instrumentarium Science Foundation (to AS), and the National Institutes of Health (grant GM-104080 to MC)

On the other hand, Gejl et al

Dosage: 0.2 to 0.3 milligrams (mg) per day, administered once daily before bedtime