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The finding of Ileibacterium as the most abundant cecal microbiome genus in every experimental group is relatively novel and may reflect experimental factors such as diet, housing conditions, and mouse strain

Specific alterations include reductions in Prevotella , Coprococcus , and Veillonellaceae , alongside overgrowth of Desulfovibrio (positively correlated with Autism spectrum disorder severity) (258), Sutterella , Ruminococcus , Clostridium , Megamonas , and Candida ( 259, 260), accompanied by an elevated Firmicutes/Bacteroidetes ratio (255)

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