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Screening evaluations included physical examination, vital signs, ECG, clinical laboratory tests (clinical chemistry, haematology, urinalysis, and serology), urine drug, cotinine, and alcohol screen, and serum pregnancy tests for females only

For cohort studies, we utilized the Newcastle-Ottawa Quality Assessment Scale for quantitative analysis, the Newcastle-Ottawa Scale was developed to assess the quality of nonrandomized studies with its design, content and ease of use directed to the task of incorporating the quality assessments in the interpretation of meta-analytic results (20)

Here are some of the most common tonsillolith myths: Myth 1: Tonsil Stones Are a Sure Indication of Poor Hygiene While poor oral care practices can contribute to tonsil stone development, its not the cause for all cases