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This likely relates to improved cellular turnover and collagen production that comes with healthier, longer telomeres

Tirzepatide-induced upregulated mRNAs were primarily associated with pathways involved in metabolic regulation, signal transduction, and endocrine function, suggesting enhanced regulation of glucose homeostasis, calcium-phosphate metabolism, and anti-inflammatory processes

Progressive mitochondrial SOD1(G93A) accumulation causes severe structural, metabolic and functional aberrations through OPA1 Down-Regulation in a mouse model of amyotrophic lateral sclerosis