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Seek urgent medical attention (call NHS 111 or 999 in an emergency) if you develop severe abdominal pain especially pain that radiates to the back (which may indicate pancreatitis) or right upper quadrant pain with fever or jaundice (which may indicate gallbladder disease)

Healthcare facilities may have institution-specific protocols that reflect local expertise and patient populations

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Mast cells play a critical role in normal immune function, responding to antigen stimuli (i.e., environmental or dietary triggers) by releasing mediators such as histamine, leukotrienes, and tryptase