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Exenatide Exenatide IR is absorbed rapidly, with maximum plasma concentrations (C max ) usually attained around 2 h following subcutaneous injection (Figure 2A and H).36,61 However, exenatide ER is encapsulated in microspheres of medical-grade poly-(D,L-lactide-co-glycolide), which ensures the gradual and extended release of the drug (Figure 2B).62 In the first few hours, 20% of the drugs total elimination or if the drugs primary target organ is the liver

Note: Headaches and mild stomach problems, which are common, can usually be managed with over-the-counter remedies