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Effects on classic cardiovascular risk factors CVOTs on GLP-1RAs Data from the major CVOTs ELIXA, SUSTAIN-6, EXSCEL, HARMONY, PIONEER 6, LEADER, REWIND, and AMPLITUDE-O [53, 54, 56, 59,60,61,62,63] support the overall safety of GLP-1RAs relative to major cardiovascular outcomes

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How GLP-1 Medications Can Enhance the Effects of Intermittent Fasting Medical weight loss drugs like semaglutide and tirzepatide were originally developed to help manage type 2 diabetes, but theyve since gained widespread use for their ability to support sustainable weight loss, improve markers of metabolic health, and be used for a variety of reasons beyond weight loss