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Materials and Methods The Institutional Review Boards at both universities approved this study, in addition to the Human Research Protection Office (HRPO) of the US Army Medical Research and Materiel Command (HRPO Log NumberA-20203.a)

Large clinical trials have shown: Approximately 20% reduction in major CV events Reduced proteinuria and slower kidney function decline Improved quality of life and energy levels Additional Systemic Effects Research also suggests benefits across other domains: Sleep quality: Weight lossdriven reductions in apnea severity Neurocognitive health: Early signals of protection against dementia, though definitive evidence is still developing Together, these outcomes position GLP-1s as a unifying therapy for overlapping metabolic, cardiovascular and renal conditions

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