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The longevity thesis is promising but unproven in humans

What Researchers Found: Nearly one-third of patients experienced adverse side effects, including liver dysfunction Life-threatening allergic reactions, including anaphylaxis Kidney damage in some cases No standard dosing guidelines exist currently Glutathione injections can quickly become a very counterproductive move

Moreover, as mitochondria play a central strategic role in the activation and mode of cell death, mitochondrial GSH has been shown to critically regulate the level of sensitization to secondary hits that induce mitochondrial membrane permeabilization and release of proteins confined in the intermembrane space that once in the cytosol engage the molecular machinery of cell death