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doi:10.2147/DMSO.S237454 [9] Ibid [10] Kurstjens S, de Baaij JH, Bouras H, Bindels RJ, Tack CJ, Hoenderop JG

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For instance, TMAO triggers NLRP3 inflammasome formation and activates NF-B signaling, Caspase-1, the PERK/Akt/mTOR pathway, and IL-1, leading to increased renal fibrosis (El-Deeb et al., 2019

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