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According to this framework, the aging effects on Polycomb targets may reflect a mechanism driven by cumulative damagewhether from exogenous insults (e.g., tobacco toxins, UV exposure) or endogenous stressors (e.g., oxidative stress, inflammation)

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Although the study can't prove cause-and-effect between cigarette smoking and cognitive decline, it adds to the body of evidence that smoking can significantly increase the risk of cardiovascular disease, including declining brain health, Dr

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