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10.1155/2020/2948282 63 LiuX.ShaoL.LiuX.JiF.MeiY.ChengY.et al (2019)

However, patients diagnosed with Mast Cell Activation Syndrome (MCAS) or severe histamine intolerance must carefully navigate what functional medicine practitioners call the 'histamine paradox.' While NAC is a widely recognized mast cell stabilizer that effectively reduces ROS-triggered degranulation, it is also fundamentally a sulfur-containing amino acid derivative