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Astrocytes and Microglia: Non-neuronal cells that modulate neurotransmitter clearance, synaptic plasticity, and inflammatory responses

In contrast, the activation of GPR109A by niacin induces Ca 2+ -dependent l-glutamate release, increasing oxidative stress in neurons of central blood pressure regulatory nuclei, leading to enhanced sympathetic excitability and elevated blood pressure (Rezq and Abdel-Rahman, 2016), which is essential for maintaining stable blood pressure levels

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doi 10.1016/j.nano.2016.08.004 84 YustaBBaggioLLKoehlerJHollandDCaoXPinnellLJet al