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Another way that glutathione blocks the activation of Tyrosinase is by reducing toxins in the cells, which causes an increase of dark pigmented melanin formation

Ansamycin derivatives such as 17-AAG (tanespimycin) and 17-DMAG (alvespimycin) reduce tau and -synuclein oligomerization in AD and PD models by promoting their degradation via the ubiquitinproteasome system