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Some of the presently contested points include (1) the source of endometrial microbiota seeding, (2) the existence of a stable, resident endometrial microbiota in the healthy state, (3) the bacterial species included in a normal/healthy endometrial microbiota (if it exists), and (4) whether uterine bacteria are transient and only associated with pathologies (reviewed in 34 )

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These findings suggest that ferroptosis is closely related to the development and progression of ADPKD, and exploring its mechanisms may offer new therapeutic hope for ADPKD

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