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The application of antioxidant therapies aimed at lowering AGE could be a helpful tool because high AGE concentrations harm vascular smooth muscle and adversely affect NO function, which in turn impairs endothelial relaxation and prevents NO action against plaque formation from the oxidized form of LDL (Saleh, 2015)

This could simplify initial treatment regimens while providing additional benefits for weight management and potentially cardiovascular risk reduction

Plant sources of protein, especially as protein concentrates such as those from seeds, such as pumpkin and sunflower seeds, and from peas, chickpeas, and other legumes, have demonstrated a capacity for elevating production of GLP-1

This dual action on satiety and gastric motility contributes substantially to their weight loss effects