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S., Grivennikov, I

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Transforming growth factor-1 (TGF-1) can induce the EMT phenotype in melanoma cells and upregulate the levels of GPX4 and SLC7A11, while gambogenic acid, a xanthone derived from traditional Chinese medicine Gamboge, can promote ferroptosis by inhibiting the SLC7A11/GPX4 pathway in melanoma cells stimulated by TGF-1

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If we rely on a one-size-fits-all approach, we risk harming patients by promoting muscle loss or triggering nutritional deficiencies

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