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The UK regulator recommends that in adults weighing less than 50 kg, clinical judgement should be employed when prescribing oral paracetamol as these patients may be at increased risk of hepatotoxicity but does not specify a dose reduction

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employed 4-Nitroquinoline N-oxide (4NQO), a known mutagen that mimics the effects of smoking and generates oxygen free radicals, to induce DNA damage in HPV-positive cells

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