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A recent metabolomics study found that male NSW exhibited higher glycoprotein acetyls (GlycA), which is a marker of chronic low-grade inflammation, along with elevated triglycerides and fatty acids, indicating a potential sex-specific link between NSW, systemic inflammation, and metabolic deregulation 153

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This mechanism would represent another antioxidant system as an alternative to GSH production to protect against oxidative stress that should be taken into account in future studies [71]