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10.1016/j.brainres.2010.03.090 Brain Res

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Children were excluded from the study if they were previously diagnosed with a genetic condition such as Fragile X syndrome, Rett syndrome, Down syndrome, tuberous sclerosis, or inborn errors of metabolism

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That placebo group regained +14.0% body weight over the next 52 weeks

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Because of their lower activation threshold at baseline 7 , MZB need mitochondrial GSH for their correct metabolic reprogramming and therefore Gclc -ablation leads to MZB loss

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