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Lancet 391, 11631173

The association of apparently unexplained features (see clinical features) and severe physical disability observed in JHS/EDS-HT broadens the spectrum of the differential to include some neurologic disorders, including multiple sclerosis, amyotrophic lateral sclerosis, hereditary and acquired sensory-motor and/or autonomic polyneuropathies, and chronic fatigue syndrome, as well as myopathies featuring JHM [30]

PMID 2828141

Strokes were the most common (only diagnosed strokes: 193, 39.04%), followed by CAD (only diagnosed CAD: 111, 31.18%), and the least number of people suffered from heart failure (HF) (only diagnosed HF: 6, 1.69%)