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In the present data, reserpine-injected rats demonstrated extensive upregulation of DRG immunohistochemical expression of CD86 in comparison with the normal group

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Although the general mechanisms of APAP-induced liver injury appear to be very similar in the 2 substrains [132], the risk for experimental design is that there is a mismatch in the substrains between WT and KO mice, which can lead to misinterpretation of the data