vitamin c serum with glutathione 25% + Clinical water soluble vitamin C for optimal effectiveness Paula's Choice Vitamin C Glutathione

Kursk State Medical University 6 3, Karl Marx Street, 305041 Kursk, Russian Federation 7 E-mail: [email protected] 8 Telephone/Fax: +7(4712) 58-81-47 9 Mobile: +7-960-699-19-92 10 Word count: 1225 11 Glutathione is a tripeptide consisting of cysteine, glycine, and glutamate, the most abundant 12 antioxidant preventing oxidative damage of cells from reactive oxygen species (ROS) [1]

Vitamin B9, for its role in SAM synthesis, is indirectly related to these methylation reactions and is necessary for its epigenetic function (, )

177 Additional clinical trials are needed to test whether oral thiamine, or thiamine derivatives such as benfotiamine, may have similarly beneficial effects

This imbalance interferes with the body's ability to detoxify the cellular microenvironment, fold proteins, replenish antioxidant levels, maintain healthy immune responses and even modulate apoptotic events