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The American College of Cardiology and American Heart Association guidelines do not currently recommend GLP-1 receptor agonists as primary lipid-lowering agents

TRT is particularly beneficial for men experiencing symptoms of testosterone deficiency, such as low energy, reduced muscle mass, and diminished libido

This review takes a deep dive into the possible factors contributing to OPLL from all aspects of metabolism, including glucose metabolism, lipid metabolism, bone and mineral metabolism, leptin, vitamin, growth hormone/IGF-1 and sex hormones, highlighting their potential roles in the onset and progression of OPLL