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However, not all studies in humans support an impact of menopause on fatty acid oxidationno significant difference was found in the rate of fatty acid oxidation (assessed by measuring plasma levels of 3-hydroxybutyrate, a byproduct of fatty acid oxidation), between pre- and postmenopausal women matched for abdominal obesity (58)

Based on our data, we believe that the RESILIENCE trial would have achieved better outcome for the patients if it were designed to treat HR+ patients with Sorafenib together with hormonal therapy versus Placebo with hormonal therapy

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[3] [4] [6] [14] [9] The goal is not to create fear around an effective class of medications