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The 55% reduction in periorbital wrinkles demonstrated in clinical studies confirms eye-area effectiveness

The success of these therapies has paved the way for the development of next-generation treatments, including multi-agonist molecules like Tirzepatide (Mounjaro/Zepbound) or Retatrutide (LY3437943) that simultaneously target several metabolic receptors to achieve improved metabolic outcomes in obese or diabetic patients [3,6]

Polyphenolic chemicals have antioxidant properties and are primarily involved in neuroprotection

These predispositions inform baseline understanding, not exact medication response predictions