The nobleman Sir Nicot having procured it to growe in his garden, where it had put forth and multiplied very greatly, was aduertifed (notified) on a daie by one of his pages, that a yoong boie kinsman of the said page, had laide (for triall sake) the said herbe, pressed, the substance and juice and altogether, upon an ulcer which he had upon his cheeke, neere unto his nose, next neighbor to a Noli me tangere, (a cancer) as having already seazed upon the cartilages, and that by the use thereof it was become marvellous well: upon this occasion the nobleman Nicot called the boie to him, and making him to continue the applying of this herbe for eight or ten days, the Noli me tangere became thoroughly kild: nowe they had sent oftetimes unto one of the king's most famous phisitions, the said boie during the time of this worke and operation to make and see the proceeding and working of the said Nicotiana, and having in charge to do the same until the end of ten days, the said phisition then beholding him, assured him that the Noli me tangere was dead, as indeed the boie never felt anything of it at any time afterward

Chewing tobacco when the composition is rough can interfere with the enamel of the teeth
Auctions Iconic T206 Honus Wagner card traced to original cigarette pack sells for $5.1M at Goldin A T206 Honus Wagner card that had remained in the same family for more than a century and was traced to its original cigarette pack in the early 1900s sold for $5,124,000 in Goldin's 2026 Winter Vintage Elite Auction
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