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Treatment discontinuation The complexity of making treatment decisions for older people with MS combined with the lack of evidence with respect to efficacy, particularly in relation to limiting neurodegeneration, raises concerns about the potential for overtreatment owing to unnecessary continuation of therapy in this population

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Protein intake in adults should not fall below 0.40.5 g/kg/d, as this can lead to muscle atrophy and functional impairments, whereas prolonged intake at or above 2 g/kg/d should be avoided due to potential adverse health effects [165]

doi: 10.1007/s12011-015-0328-1 74