A 2022 study published in the journal Diabetes, Obesity and Metabolism showed that one year after stopping semaglutide, individuals regained two-thirds of the weight they'd lost while on the medication

methotrexate is often first-line, combined with short-term corticosteroids [18] [19] Biological therapies : TNF inhibitors (such as adalimumab, etanercept) or other biologics for inadequate response to conventional DMARDs JAK inhibitors : Newer oral medications like tofacitinib for refractory cases Regular monitoring : Blood tests to assess disease activity and medication safety Allied health professional input plays a crucial role: Physiotherapy : Exercise programmes, joint protection techniques, mobility aids Occupational therapy : Adaptations to daily activities, assistive devices, workplace modifications Podiatry : Foot care and orthotic provision for lower limb arthritis When to contact your GP : New or worsening joint pain, swelling, or stiffness Morning stiffness lasting more than 30 minutes (suggestive of inflammatory arthritis) Joint symptoms affecting daily activities or sleep Inadequate symptom control with current treatments Side effects from arthritis medications When to seek urgent medical attention : A hot, acutely swollen joint (possible septic arthritis) Joint symptoms accompanied by fever or feeling systemically unwell Patients can access NHS services through GP referral, and many areas offer self-referral to physiotherapy services (check local NHS provision)

Semaglutide (marketed under the brand name Wegovy) and liraglutide (Saxenda) did lead to weight loss, but it was significantly less at 15% and 8%, respectively
Meanwhile, lower-income patients, people of color and those who are not tech-savvy may not be getting the help they need, Moore said