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Lancet Oncol 13(11):11611170 Moore MJ et al (2007) Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group

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Examples include: Insulin regulates blood sugar in diabetes GLP-1 medications (semaglutide, tirzepatide) used for diabetes and weight management Calcitonin used in bone metabolism disorders These medications underwent years of clinical trials and regulatory review before becoming approved treatments