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For my patients facing increased cancer risk due to genetic factors, I encourage them to lean into their faith and find peace in knowing that while we cannot change our genetics, we have tremendous power to influence how those genes are expressed

Functional sepiapterin reductase is a homodimeric enzyme which first converts 6-pyruvoyltetrahydropterin to 1-hydroxy-2-oxopropyltetrahydropterin, which is then reduced to 1-oxo-2-hydroxypropyltetrahydropterin, and then finally to 5,6,7,8-tetrahydrobiopterin, BH 4