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Summary: GLP-1 receptor agonists can produce clinically significant weight loss without structured exercise, though combining medication with physical activity optimises outcomes and preserves muscle mass

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Theres also a significant and growing number of people who turn to these drugs for what I refer to as vanity pounds typically a relatively healthy person with maybe an extra 10 or 20 pounds theyd like to lose, but nothing thats posing any notable health risks

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