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However, we do not fully understand why these aging hallmarks occur in the first place, and therefore there have been no proven solutions via human randomized clinical trials to improve or correct aging hallmarks in aging humans. The aging hallmarks that improved are mitochondrial dysfunction, altered intercellular communication, nutrient sensing, loss of proteostasis, genomic instability, cellular senescence and stem cell fatigue

Essentially, L-Carnitine acts as a transporter, carrying fatty acids to the parts of your cells that burn fat for fuel

alternatively, you can remain on a lower maintenance dose

doi:10.1001/jamaoto.2014.632