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After a month-long break, a conservative approach often involves restarting at a lower dosetypically the starting dose of 2.5 mg weekly or one step below the previous maintenance dosethen re-escalating according to the standard titration schedule

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The prognostic importance of different definitions of worsening renal function in congestive heart failure

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Any psoriasis improvement with GLP-1 therapy likely occurs indirectly through substantial weight loss, which reduces systemic inflammation and pro-inflammatory adipokines

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