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Other recognised contributors to RLS include chronic kidney disease (particularly uraemia), pregnancy, and certain medications such as some antidepressants (SSRIs/SNRIs), antipsychotics, and dopamine antagonists (including anti-nausea medications like metoclopramide)

450,451,452 A healthy diet and regular physical exercise including approximately 30 minutes of exercise at least five days a week leads to activation of muscle cells that increase AMPK activity, thereby inactivating TCB1D1 and promoting GLUT4 translocation to cellular membrane, in addition to increasing glucose uptake that increases insulin reactivity

Its use is limited to analytical investigation, receptor-mediated signaling studies, and cellular pathway modeling conducted under structured experimental protocols

We noted that formal meta-analyses of endometriosis biomarkers were largely absent, and will likely remain challenging due to the heterogeneity in study designs and data collection records that we highlighted above, limiting the reusability of available information